Formula 303 Review – Is It Worth It? [2022 Update]

Formula 303


  • Helps Insomnia
  • Induces calm
  • Reduces anxiety
  • Reduces stress-related body pains


  • Vomiting
  • Dizziness
  • Tiredness
  • Drowsiness
  • Upset stomach
  • Trouble breathing
  • Interaction with other medicines


An all-natural relaxant, Formula 303 claims to treat stress and anxiety, cure restlessness and provide relief from body aches. The supplement claims to kill many birds by using just three ingredients. The formula does appear to help with anxiety to some extent. But, the safety profile of passiflora and valerian root is not fully established yet. We advise users to check with their healthcare practitioners before adding this supplement to their diet. Besides, there are better nootropic supplements in the market that have extensive research in their favor. We suggest looking for one of those.

In this often-chaotic world, stress and anxiety have become part and parcel of our lives. If you too are suffering from sleeplessness and restlessness, then you might have spent time and energy in finding a supplement that can provide relief. 

Formula 303 is one such product that promises to provide a cure from stress and anxiety. It is an all “natural relaxant” that eases muscle spasm, stress and promotes overall mental well-being. 

Curious by the above claims?

Our research team delved deeper to uncover the facts on this supplement. Let’s then take a look at what we found out.

What is Formula 303?

An all-natural relaxant, Formula 303 claims to treat stress, tension and muscle spasm. As a by-product of treating anxiety and stress, it also provides relief from leg cramps, restlessness, muscle and tissue pain, low back pain, menstrual cramps, neck and shoulder pain.

About Manufacturer

Formula 303 is manufactured by Dee Cee Laboratories which is based out of Tennessee, USA. They manufacture a host of other supplements and vitamins. 

An added advantage for users looking for natural products is that the manufacturer claims that all their supplements are created in-house and are free of artificial additives and preservatives.

Formula 303 Claims

Dee Cee Labs claims the below use of their supplement:

  • It provides relief from anxiety and stress
  • It helps with sleep disorders
  • It alleviates muscle spasm
  • It helps with jitters and nervousness

Formula 303 Ingredients Analysis

This relaxant supplement has a simpler formulation and uses only three ingredients. Let’s take a closer look and see how they can affect the human body.

Valerian root

Valerian is an herb which is traditionally used to reduce stress caused by anxiety. Its oral consumption helps in relaxing the mind and inducing sleep. 

It is used by many as a natural alternative to a ‘sleeping pill’ and an herbal remedy for treating:

  • Stress
  • Headaches 
  • Trembling

Apart from the traditional use, limited scientific data is available on the use and side-effects of this herb. 

The available data indicates that Valerian works by increasing the level of GABA in the brain, a chemical that works by prohibiting stress-related brain signals which in turn induces calmness. 

A study done by Phytotherapy Research concludes that there can be minor improvements in anxiety, but more advanced studies are required to assess the long-term effect. 

However, another study published in Science Direct reported no significant improvement in insomnia patients. 

Key point: Valerian root is considered safe by the FDA, but there can be mild side-effects like headache, dizziness, upset stomach and restlessness. Since the Valerian root is known to cause drowsiness, users must practise caution before driving. Do not combine Valerian with other sedatives, antidepressants or alcohol as it could lead to more pronounced effects.


Passiflora or Passionflower is native to America. There are many species of this plant and one of them, Passiflora incarnata, is used by some people to treat sleep issues and anxiety. 

The chemicals in Passionflower are known to induce a calming effect, help with sleep and reduce muscle spasm. (1)

It is known to increase the level of GABA, which in turn helps to reduce stress.

In a study published in Phytotherapy Research, participants that were given passionflower tea for seven days showed improvements in anxiety.

Key point: Since Passiflora works by reducing brain-activity and inducing sleep, it can be potentially dangerous to consume before driving. According to a study by the National Centre for Complementary and Integrative Health in some people, Passiflora supplement can lead to dizziness and confusion. 

Magnesium carbonate

Magnesium is an essential mineral required for the normal functioning of body cells, muscles and bones. A person consuming a well-balanced diet will normally get the optimum level of magnesium from the food. 

Its deficiency can be caused due to a poor diet, alcohol consumption or a disease.

Key point: Side-effects of a magnesium supplement include upset stomach and diarrhea. For better absorption, always try to take it along with the meal. Over consumption can cause magnesium toxicity which might lead to nausea, vomiting, trouble breathing and severe diarrhea. 

Are Formula 303 Ingredients Safe And Effective?

The recipe for Formula 303 is pretty simple as the supplement uses only three ingredients. We have individually studied and listed the benefits and risks associated with each one above. 

In general, the ingredients appear safe to consume by healthy beings, and they do seem to provide relief to the users who face daily struggles due to anxiety. 

That being said, medical studies available on Valerian root give out mixed results in treating insomnia. We need large scale clinical trials to provide conclusive results on its long-term safety and use. 

FDA earlier approved Passiflora as an OTC sedative for treatment of sleep disorders but withdrew when it did not find sufficient evidence supporting its safety and effectiveness (1).

In short, readers should assess beforehand if they are allergic to any of the above two herbs.

A magnesium supplement is usually safe to consume, but if your body is already at an optimum level, then there's no point of consuming it further. 

Also, the official website mentions the proportion of each ingredient but does not mention the exact dose of each element which is important to find the potency of each dose. 

The minimum dose recommended on the official website is about six tablets a day. We feel that it is an awful number of pills to consume in a single day and calls for an additional effort to bear it in mind.

Warnings for Formula 303 Users

The official website states to seek the advice of a health professional before using this product if you are pregnant or nursing a baby.

The official website doesn’t mention if children should use it, but our research suggests against it.

How to Take Formula 303?

The official website states specific doses depending on the issue at hand:

  • As a muscle relaxant: Two tablets every three hours until relief. Then two tablets with each meal and two at bedtime.
  • For tension and stress: Two tablets with each meal and two at bedtime.

Does Formula 303 Provide 100% BrainPower?

There’s no arguing the fact that a good sleep leads to better retention and a calm mind. Formula 303 does prove to be an effective supplement for reducing sleep irregularities. Consequently, users will feel clear-headed and more relaxed.  

However, when it comes to brainpower, we found that the ingredients do not directly target the brain’s functions. Some indirect benefits are realised due to its calm-inducing effects. 

Customers have reported that after a few days of consumption, their sleep pattern improved and also helped them to relax in general. Regarding anxiety, we did not find sufficient reviews or evidence to back the claim.

In essence, customers will experience better sleep which might restore the brain performance to its natural and calmer state. However, individuals should not expect improvements in cognition and learning as the formula doesn’t contain any active nootropic ingredients.

Customers Reviews

I'm a skeptic when it comes to things like natural supplements, but on the recommendation of a friend, I decided to give Formula 303 a try. I found it to be helpful for relaxation, but not much for helping with anxiety (the reason I purchased it). My husband found that it helped him with his muscle spasms in his back. We both will continue to use it as we feel the benefits are worth the cost. The tablets do have an offensive smell though.

K Baumle

I had horrible Headaches with this. I don't know if it is even related but my friend who was 45 years old was taking these before i started and she died of having two non-hemorrhagic strokes within hours of each one. she mentioned having headaches as well when i was with her in dec. i stopped taking related to her stroke/HA or not, scared me to use anymore and didnt like the HA's

Travel RN

I have used these on and off for two months. I never had any real relief that was noticeable from tensed muscled or anxiety. Moods did not improve. I urge those to take the reviews with only a little seriousness…lots of biased and some are having placebo effects I know! This is the fifth natural” supplement I have tried online and they all are a load of crap!


Where to Buy Formula 303?

Formula 303 is available for purchase from limited healthcare professionals and a few online retailers like Amazon and Pure Formulas.

  • One bottle of Formula 303 (250 tablets) costs $ 68

Return Policy & Money-Back Guarantee

The official website does not specify any return or refund policy. 

Is Formula 303 A Good Nootropic For You?

If you are facing sleep or restlessness issues, then this product can help you manifolds. However, with any sleep-inducing supplements, we need to be cautious of the addiction that can occur in the long-term.

Some customers have reported their dependency on this supplement for falling asleep. Hence, we suggest, if you are going to use it then do so for short-term treatment.

If your need is only to improve the quality of your sleep, we insist on first resorting to natural options. A good exercise of about 30 minutes each day, 4 to 5 days a week will go a long way to relax your mind and reduce sleep irregularities. If you still don’t get any relief, then you may use Formula 303 and see if it works well for you. 

It is important to diagnose your health concern first. If you are looking for a supplement that will provide an all-round benefit to your brain and related functions including sleep issues, then we suggest you take a look at other well-founded supplements. One of them, proven for its adequacy is the Mind Lab Pro which is known to support overall brain health.

Mind Lab Pro is an effective and safe supplement that helps you remain active in your day to day life and improve your sleep and cognitive faculties. Scientific studies support the use and safety of its ingredients.

So, if this looks like the kind of supplement you are looking for, then do go through our detailed review on the same here. The company is offering 30 days 100% money-back guarantee if you’re not satisfied with the supplement.

Here’s a brief comparison between the two products that can help you identify which fits best for you.

Comparison Table

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Formula 303

Formula 303

Mind Lab Pro Review

Mind Lab Pro

Support Memory?

Encoding, Storage, Recall, Learning, Test Taking

Support Brain Energy?

Mental agility, quick thinking and focus

Supports Mindset

Mood balance, Stress resistance, Relaxation, Creativity, Motivation

Supports Focus

Supports Brain Protection

Fights toxins and unhealthy structural changes that degrade the brain over time.

Supports Performance

Speed, Process, Attention, Focus, Verbal

Supports Structural

Injury repair, Fluid membranes, Neurogenesis, Anti-aging, Fight depression

Meets mental performance demand

From day to day and hour to hour

Helps with immediate and long-term brain health and function

Free from stimulants and additives

Side Effects

Vomiting, Nausea, Drowsiness, Upset stomach, Dizziness, etc.

No Potential Side Effects


Per Bottle



Free Shipping


Limited Countries


Money Back Guarantee

No Money Back Guarantee

30 Days


When your sleep pattern improves, positive results show in other bodily functions too. Formula 303 works on similar lines; it mitigates insomnia and anxiety, hence reducing body aches related to stress and tension.

But aside from its benefits, there are potential side-effects involved, so, our word of caution here is not to use it as a prescription medicine for sleep disorders. 

Please note, our research team does its best to provide you with facts based on our vast experience and in-depth research of scientific studies and customer reviews. However, this is not meant to be a piece of medical advice. 

When deciding on a supplement, read through the positives and negatives of each ingredient and then decide what works best for your body. Knowing the potential side-effects beforehand will help you make a better choice!

If you are in search of a nootropic that performs its function without any side effects, then we recommend Mind Lab Pro. It is touted as the cleanest brain supplement that has no additives and is 100% vegan - interested to learn more about it? 

Last Updated On: June 23rd, 2022

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